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Introduction to nervous
system (NS) pathology; clinical features of neuronal disease;
syndromes associated with NS disease (meningitis, acute encephalitis,
meningo-encephalitis, post-viral encephalitis, peripheral neuropathies);
viruses most commonly involved in NS infections (including Rabies);
viruses less commonly involved in NS disease, diseases with multiple
aetiologies (e.g. Guillain-Barre syndrome); diagnosis of NS infection
(serology and significance of CSF/serum antibody levels, culture,
limitations of conventional diagnostic methods, and novel techniques);
treatment and prevention (vaccines and antivirals); safety aspects
of dealing with NS infections.
Conventional viruses and "slow" NS disease (e.g. measles,
polyomas, retroviruses), significance in the immunocompromised
host; unconventional agents in man and animals (Prions e.g. CJD,
Kuru, Scrapie, BSE, nvCJD); pathology and clinical features of
"slow virus"/prion infections; modes of transmission;
problems of diagnosis; suggested structure and composition of
Prions; prevention of disease; safety aspects and restrictions.
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